{"id":130770,"date":"2018-10-31T07:15:37","date_gmt":"2018-10-30T22:15:37","guid":{"rendered":"http:\/\/ameba.jp.net\/dietjohokyoku\/?guid=5468a42ab4a02b57b0d99fbb7daeda70"},"modified":"2018-10-31T07:15:37","modified_gmt":"2018-10-30T22:15:37","slug":"post-0","status":"publish","type":"post","link":"http:\/\/harsio.net\/blog\/?p=130770","title":{"rendered":"\u3010\u30c7\u30d6\u306b\u6717\u5831\u3011\u4f53\u5185\u306e\u8102\u80aa\u306e3\u5206\u306e1\u309218\u65e5\u9593\u3067\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u767a\u898b\u3055\u308c\u308b"},"content":{"rendered":"
\n
1: \u540d\u7121\u3057\u30c0\u30a4\u30a8\u30c3\u30c8<\/span> 2018\/10\/30(\u706b) 15:28:37.72 ID:CAP_USER<\/span><\/dt>\n
\n
\u300cFGFBP3\u300d\u3068\u3044\u3046\u5929\u7136\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f7f\u3063\u305f\u6cbb\u7642\u309218\u65e5\u9593\u884c\u3063\u305f\u30de\u30a6\u30b9\u304c\u3001\u4f53\u5185\u306e\u8102\u80aa\u306e3\u5206\u306e1\u3092\u6e1b\u3089\u3059\u3053\u3068\u306b\u6210\u529f\u3057\u305f\u3068\u3001\u30a2\u30e1\u30ea\u30ab\u306e\u30b8\u30e7\u30fc\u30b8\u30bf\u30a6\u30f3\u306b\u3042\u308b\u304c\u3093\u30bb\u30f3\u30bf\u30fc\u300cGeorgetown Lombardi Comprehensive Cancer Center\u300d\u306eAnton Wellstein\u6c0f\u3089\u7814\u7a76\u30c1\u30fc\u30e0\u304c\u767a\u8868\u3057\u307e\u3057\u305f\u3002

Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism | Scientific Reports
https:\/\/www.nature.com\/articles\/s41598-018-34238-5<\/a>

Obese mice lose a third of their fat using a natural protein -- ScienceDaily
https:\/\/www.sciencedaily.com\/releases\/2018\/10\/181029084038.htm<\/a>

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FGFBP3\u306f\u7dda\u7dad\u82bd\u7d30\u80de\u5897\u6b96\u56e0\u5b50(FGF)\u306e1\u3064\u3067\u3042\u308b\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8cea(BP)\u3067\u3001\u30a4\u30e2\u30e0\u30b7\u304b\u3089\u30d2\u30c8\u307e\u3067\u3001\u3055\u307e\u3056\u307e\u306a\u751f\u304d\u7269\u306e\u4f53\u306b\u5b58\u5728\u3057\u3001\u300c\u50b7\u306e\u4fee\u5fa9\u300d\u300c\u7d30\u80de\u306e\u6210\u9577\u306e\u5236\u5fa1\u300d\u306a\u3069\u5e45\u5e83\u3044\u751f\u7269\u5b66\u7684\u30d7\u30ed\u30bb\u30b9\u306b\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u3044\u304f\u3064\u304b\u306eFGF\u306f\u30db\u30eb\u30e2\u30f3\u306e\u3088\u3046\u306a\u50cd\u304d\u3092\u3059\u308b\u3053\u3068\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002

BP1\u3001BP2\u3001PB3\u306f\u30b7\u30e3\u30da\u30ed\u30f3\u3068\u547c\u3070\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308a\u3001FGF\u3068\u7d50\u5408\u3057\u3066\u3001\u4f53\u306e\u3055\u307e\u3056\u307e\u306a\u90e8\u5206\u3067\u6d3b\u52d5\u3059\u308b\u3082\u306e\u3002BP1\u306f\u3044\u304f\u3064\u304b\u306e\u304c\u3093\u3067\u5897\u52a0\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u300c\u3042\u308b\u7a2e\u306e\u304c\u3093\u7d30\u80de\u306e\u6210\u9577\u306f\u3001FGF\u306e\u904e\u5270\u4f9b\u7d66\u3068\u95a2\u4fc2\u3057\u3066\u3044\u308b\u300d\u3068\u3044\u3046\u3053\u3068\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002Wellstein\u6c0f\u306f\u9577\u3044\u9593\u3001BP1\u306e\u907a\u4f1d\u5b50\u3092\u7814\u7a76\u3057\u3066\u304a\u308a\u3001\u305d\u306e\u5f8c\u3001\u7814\u7a76\u8005\u305f\u3061\u306fBP3\u306b\u3064\u3044\u3066\u3082\u7814\u7a76\u3092\u884c\u3046\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002

\u305d\u3057\u3066\u7814\u7a76\u8005\u305f\u3061\u306f\u3001\u30b7\u30e3\u30da\u30ed\u30f3\u304cFGF19\u3001FGF21\u3001FGF23\u3068\u3044\u30463\u3064\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u7d50\u5408\u3059\u308b\u3053\u3068\u304c\u3001\u4ee3\u8b1d\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u767a\u898b\u3002FGF19\u3068FGF21\u306e\u30b7\u30b0\u30ca\u30eb\u306f\u70ad\u6c34\u5316\u7269(\u7cd6)\u3084\u8102\u8cea(\u8102\u80aa)\u306e\u8caf\u8535\u3084\u4f7f\u7528\u3092\u5236\u5fa1\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u307e\u305f\u3001FGF23\u306f\u30ea\u30f3\u9178\u4ee3\u8b1d\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\u3066\u3044\u307e\u3057\u305f\u3002

\u300c\u79c1\u305f\u3061\u306f\u3001BP3\u304c\u4ee3\u8b1d\u8abf\u7bc0\u306b\u5bfe\u3057\u3066\u8457\u3057\u3044\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u300d\u300cBP3\u30b7\u30e3\u30da\u30ed\u30f3\u304c\u5897\u52a0\u3059\u308c\u3070\u3001\u30b7\u30b0\u30ca\u30eb\u306e\u5897\u52a0\u306b\u3088\u3063\u3066FGF19\u3084FGF21\u306e\u5f71\u97ff\u3082\u5927\u304d\u304f\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u304c\u3001BP3\u304c\u70ad\u6c34\u5316\u7269\u3084\u30ea\u30f3\u9178\u306e\u4ee3\u8b1d\u306e\u5f37\u529b\u306a\u300e\u30c9\u30e9\u30a4\u30d0\u30fc\u300f\u3067\u3042\u308b\u7406\u7531\u3067\u3059\u3002\u30cb\u30e5\u30fc\u30e8\u30fc\u30af\u3067\u3088\u308a\u591a\u304f\u306e\u30bf\u30af\u30b7\u30fc\u304c\u5229\u7528\u53ef\u80fd\u306b\u306a\u308c\u3070\u3001\u79fb\u52d5\u3092\u5fc5\u8981\u3068\u3059\u308b\u5168\u3066\u306e\u4eba\u3092\u9001\u308a\u5c4a\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u300d\u3068Wellstein\u6c0f\u306f\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002

\u3055\u3089\u306b\u3001Wellstein\u6c0f\u306f\u300c\u4ee3\u8b1d\u304c\u4e0a\u304c\u308c\u3070\u3001\u8840\u4e2d\u306e\u7cd6\u3084\u809d\u81d3\u3067\u51e6\u7406\u3055\u308c\u308b\u8102\u80aa\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u306b\u5909\u3048\u3089\u308c\u3001\u8caf\u84c4\u3055\u308c\u307e\u305b\u3093\u300d\u300c\u307e\u305fFGF21\u306e\u4ed5\u4e8b\u306f\u8102\u80aa\u306e\u5206\u89e3\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3053\u3068\u306b\u3042\u308a\u3001\u65e2\u306b\u3042\u308b\u8102\u80aa\u306e\u8caf\u8535\u306b\u3064\u3044\u3066\u3082\u540c\u69d8\u306e\u3053\u3068\u304c\u3044\u3048\u307e\u3059\u300d\u3068\u7d9a\u3051\u307e\u3057\u305f\u3002

\u4eca\u56de\u306e\u7814\u7a76\u7d50\u679c\u306f\u79d1\u5b66\u8005\u305f\u3061\u3092\u8208\u596e\u3055\u308c\u308b\u3082\u306e\u3067\u3042\u3063\u305f\u3082\u306e\u306e\u3001FGFBP3\u304c\u4eba\u9593\u306e\u4ee3\u8b1d\u969c\u5bb3\u6cbb\u7642\u3067\u3082\u540c\u69d8\u306b\u52b9\u679c\u304c\u3042\u308b\u306e\u304b\u3069\u3046\u304b\u3092\u8abf\u3079\u308b\u524d\u306b\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3060\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\"no<\/a>
https:\/\/gigazine.net\/news\/20181030-obese-mice-fat-natural-protein\/<\/a> <\/div>
\n<\/dd>\n<\/div>\n
\n\u7d9a\u304d\u3092\u8aad\u3080<\/a>\n\n\n","protected":false},"excerpt":{"rendered":"

1: 名無しダイエット 2018\/10\/30(火) 15:28:37.72 ID:CAP_USER<\/p>\n

「FGFBP3」という天然タンパク質を使った治療を18日間行ったマウスが、体内の脂肪の3分の1を減らすことに成功したと、アメリカのジョージタウンにあるがんセンター「Georgetown Lombardi Comprehensive …<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3,128],"tags":[],"_links":{"self":[{"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=\/wp\/v2\/posts\/130770"}],"collection":[{"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=130770"}],"version-history":[{"count":1,"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=\/wp\/v2\/posts\/130770\/revisions"}],"predecessor-version":[{"id":130772,"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=\/wp\/v2\/posts\/130770\/revisions\/130772"}],"wp:attachment":[{"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=130770"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=130770"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/harsio.net\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=130770"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}